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Nifedipine is a medication used to manage angina, high blood pressure, Raynaud's phenomenon, and premature labor. It is one
of the treatments of choice for Prinzmetal angina. It may be used to treat severe high blood pressure in pregnancy. Its use in
preterm labor may allow more time for steroids to improve the baby's lung function and provide time for transfer of the mother
to a well-qualified medical facility before delivery. In the present work, an attempt has been made to develop Sublingual tablets
of Nifedipine chitosan, Locust bean gum and crospovidone were employed as super disintegrating agents to enhance the
solubility and dissolution rate of selected drug molecule. All the formulations were prepared by direct compression method
using 6mm punch on 8 station rotary tablet punching machine. The blend of all the formulations showed good flow properties
such as angle of repose, bulk density, tapped density. The prepared tablets were shown good post compression parameters and
they passed all the quality control evaluation parameters as per I.P limits. Among all the formulations NDPN4 formulation
showed maximum % drug release i.e., 98.73 % in 8 min hence it is considered as optimized formulation. The NDPN4
formulation contains locust bean gum as super disintegrate in the concentration of 15 mg
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